Jerry L Nadler Selected Research

Obesity

10/2014	12-lipoxygenase promotes obesity-induced oxidative stress in pancreatic islets.
9/2014	Adipose tissue 12/15 lipoxygenase pathway in human obesity and diabetes.
8/2014	Bariatric surgery decreases monocyte-platelet aggregates in blood: a pilot study.
12/2013	STAT4 deficiency reduces obesity-induced insulin resistance and adipose tissue inflammation.
7/2013	12- and 15-lipoxygenases in adipose tissue inflammation.
2/2012	Accelerated atherosclerosis in Apoe-/- mice heterozygous for the insulin receptor and the insulin receptor substrate-1.
1/2011	Evidence for activation of inflammatory lipoxygenase pathways in visceral adipose tissue of obese Zucker rats.
12/2010	Differential expression and localization of 12/15 lipoxygenases in adipose tissue in human obese subjects.
3/2010	Valsartan protects pancreatic islets and adipose tissue from the inflammatory and metabolic consequences of a high-fat diet in mice.
9/2009	12/15-lipoxygenase products induce inflammation and impair insulin signaling in 3T3-L1 adipocytes.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Jerry L Nadler Research Topics

Disease

31	Inflammation (Inflammations) 10/2023 - 05/2003
20	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2022 - 06/2002
18	Insulin Resistance 10/2023 - 05/2002
18	Atherosclerosis 10/2023 - 09/2003
12	Obesity 10/2014 - 10/2007
11	Type 2 Diabetes Mellitus (MODY) 01/2017 - 05/2002
10	Hyperglycemia 11/2016 - 12/2003
4	Glucose Intolerance 01/2016 - 03/2004
4	Peripheral Nervous System Diseases (PNS Diseases) 08/2013 - 09/2010
3	Atherosclerotic Plaque (Atheroma) 02/2023 - 06/2007
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 05/2022 - 01/2006
3	Infections 02/2020 - 01/2005
3	Diabetic Neuropathies (Diabetic Neuropathy) 08/2013 - 09/2010
3	Diabetic Nephropathies (Diabetic Nephropathy) 06/2007 - 12/2003
2	Thrombosis (Thrombus) 01/2021 - 07/2017
2	Body Weight (Weight, Body) 03/2016 - 03/2004
2	Pneumonia (Pneumonitis) 09/2012 - 10/2009
2	Acute Lung Injury 09/2012 - 10/2009
2	Disease Progression 03/2011 - 04/2003
2	Cardiovascular Diseases (Cardiovascular Disease) 12/2010 - 10/2002
2	Diabetic Angiopathies (Diabetic Angiopathy) 09/2004 - 09/2003
2	Hypertrophy 11/2002 - 03/2002
1	Metabolic Diseases (Metabolic Disease) 11/2021
1	Vascular System Injuries 07/2017
1	Wounds and Injuries (Trauma) 01/2017
1	Autoimmune Diseases (Autoimmune Disease) 01/2015
1	Edema (Dropsy) 09/2012
1	Hyperinsulinism (Hyperinsulinemia) 02/2012
1	Chronic Disease (Chronic Diseases) 07/2011

Drug/Important Bio-Agent (IBA)

25	Arachidonate 15-Lipoxygenase (Arachidonate 15 Lipoxygenase)IBA 01/2022 - 03/2004
19	Insulin (Novolin)FDA Link 01/2022 - 06/2002
16	Glucose (Dextrose)FDA LinkGeneric 10/2023 - 12/2003
14	CytokinesIBA 10/2023 - 06/2002
8	EnzymesIBA 11/2021 - 03/2007
8	Arachidonate 12-Lipoxygenase (12 Lipoxygenase)IBA 01/2021 - 03/2002
6	AcidsIBA 07/2017 - 03/2002
6	lisofyllineIBA 05/2012 - 11/2003
5	CholesterolIBA 10/2023 - 10/2008
5	Apolipoproteins E (ApoE)IBA 02/2023 - 10/2004
5	Proteins (Proteins, Gene)FDA Link 10/2017 - 03/2002
5	LipidsIBA 07/2017 - 03/2002
4	Interleukin-12 (IL 12)IBA 10/2023 - 05/2004
4	Arachidonic Acid (Vitamin F)IBA 09/2010 - 03/2002
3	Sorbitol (Yal)FDA Link 04/2012 - 10/2007
3	ApolipoproteinsIBA 02/2012 - 10/2004
3	LipoxygenasesIBA 01/2011 - 05/2008
3	Streptozocin (Streptozotocin)FDA Link 06/2010 - 05/2003
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 06/2007 - 09/2003
2	EicosanoidsIBA 01/2021 - 01/2014
2	NF-kappa B (NF-kB)IBA 02/2020 - 05/2008
2	Interferon Type IIBA 02/2020 - 10/2017
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2017 - 05/2006
2	Blood Glucose (Blood Sugar)IBA 11/2016 - 09/2010
2	Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA 03/2016 - 03/2002
2	Mitogen-Activated Protein KinasesIBA 08/2013 - 04/2012
2	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 05/2012 - 07/2006
2	Aldehyde Reductase (Aldose Reductase)IBA 04/2012 - 10/2007
2	p38 Mitogen-Activated Protein KinasesIBA 07/2011 - 03/2002
2	Fingolimod Hydrochloride (FTY720)FDA Link 03/2011 - 04/2003
2	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA 01/2011 - 05/2008
2	Messenger RNA (mRNA)IBA 06/2010 - 05/2006
2	Oxidants (Oxidizing Agents)IBA 01/2006 - 09/2003
2	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 01/2006 - 09/2004
2	Angiotensin IIIBA 12/2003 - 03/2002
2	Fibronectins (Fibronectin)IBA 11/2002 - 03/2002
1	STAT4 Transcription FactorIBA 10/2023
1	ML355IBA 01/2021
1	Viral ProteinsIBA 02/2020
1	Antiviral Agents (Antivirals)IBA 10/2017
1	Thrombin FDA Link 07/2017
1	Phospholipids (Phosphatides)FDA LinkGeneric 07/2017
1	Phosphatidylethanolamines (Cephalins)IBA 07/2017
1	Complement C1 (Complement 1)IBA 01/2017
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2017
1	InterferonsIBA 01/2017
1	AnaphylatoxinsIBA 01/2017
1	CCR2 ReceptorsIBA 01/2017
1	Peptides (Polypeptides)IBA 01/2017
1	6alpha-ethyl-23(S)-methylcholic acidIBA 03/2016
1	Glucagon (Glukagon)FDA Link 03/2016
1	Glucagon-Like Peptide 1 (GLP 1)IBA 03/2016
1	Letrozole (Femara)FDA LinkGeneric 01/2016
1	Estradiol (Delestrogen)FDA LinkGeneric 01/2016
1	Estrogens (Estrogen)FDA Link 01/2016
1	AutoantibodiesIBA 01/2015
1	Lipoxygenase InhibitorsIBA 08/2013
1	LipopolysaccharidesIBA 09/2012
1	INGAP peptideIBA 05/2012
1	Peptide FragmentsIBA 05/2012
1	Insulin Receptor Substrate ProteinsIBA 02/2012
1	Insulin ReceptorIBA 02/2012
1	Drug CombinationsIBA 07/2011
1	baicaleinIBA 07/2011
1	FlavonoidsIBA 07/2011
1	Reducing AgentsIBA 01/2011
1	Protein Isoforms (Isoforms)IBA 12/2010

Therapy/Procedure

4	Therapeutics 06/2015 - 12/2007
2	Islets of Langerhans Transplantation 01/2005 - 01/2004
1	Lasers (Laser) 01/2017
1	Bariatric Surgery 08/2014